Which term refers to the involvement with a substance despite its harmful effects?

The term that refers to the involvement with a substance despite its harmful effects is addiction. This concept is characterized by the compulsive use of a substance, even when it leads to negative consequences such as physical or mental health issues, social problems, or disruptions in daily life. Addiction signifies a loss of control over substance use, indicating a profound relationship with the substance that overrides an individual’s capacity to make healthier choices.

In addiction, there is often a persistent desire or unsuccessful efforts to cut down or control use, cravings, and a tolerance build-up, which further emphasize the substance's detrimental effects. Understanding addiction in this context helps professionals in the field develop more effective interventions and support strategies. Recognizing the underlying issues associated with addiction is crucial for promoting recovery and health.